The woman, Christina Baca, 39, walked away from a vehicle being driven by her husband Edward Baca, 58, at about 5 p.m. Saturday as they were in the area of North Fairway Drive and State Route 119, in the Hoodsport area of Mason County.
According to her husband, Christina walked to the area of the Hoodsport Trail Head. About 45 minutes later, she called her husband on her cell phone and said she was going to be walking home.
At about 10:50 a.m. Sunday, the husband called to report that his wife never returned home, but that she has done this before.
The husband also told deputies that Christina Baca is suffering from being bipolar and had been drinking alcohol Saturday afternoon.
A Mason County sheriff's sergeant searched the area where she was last seen with a bloodhound, and officials said there is a possibility that someone may have provided Christina Baca a ride.
About 20 searchers are now combing the area, looking for her.
Christina Baca, also known as Christina Skaggs, is described as a white woman, standing about 5-feet-tall, weighing about 125 pounds, with shoulder-length brown hair and green eyes. She was last seen wearing bright pink pajama bottoms and a green jacket.
Anyone with information on her whereabouts is asked to call the Mason County Sheriff's Office at (360)427-7761.