Now, the assassin's former lover is speaking out, and she insists Lee Harvey Oswald was framed.
"I can assure you that Lee Harvey Oswald loved President Kennedy," said Judyth Vary Baker, who dated Oswald. "He wasn't the president's assassin."
Baker was just 19-years old and working on cancer research when she met and fell in love with Oswald.
"We were immediately attracted to each other," she said. "He was only 23."
Baker said they soon became lovers, and later she learned the cancer project she was working on was to develop a biological weapon to kill Cuba's Fidel Castro.
She claims Oswald confided in her.
"I learned that he was a spy in Russia for the U.S.," she said.
Now 70 years old, Baker is in Seattle to promote her new book, called "Me and Lee: How I came to Know, Love and Lose Lee Harvey Oswald."
In the book, she describes bonding with Oswald over chess and a love of Russian literature.
She insists Oswald entered an assassination group trying to kill Castro and encountered elements that loathed America's president as much as Cuba's.
She said Oswald called her 37 hours before the Kennedy assassination, suggesting he was going to be framed.
"He said, 'I'm afraid I've told you too much and your life might be in danger,'" she said.
Two days later, Baker said she watched her lover gunned down on television.
"I wanted to kill myself," she said.
Baker said she's not a conspiracy theorist and insists she's paid a price for sharing her past.
"If I'd only said that Lee Oswald killed Kennedy I could have been a rich woman. Instead, I'm hoping I can get enough money for new glasses," she said.
Baker will discuss her new book Tuesday night at 7:30 p.m. in room 201 of the Washington Convention Center.