The blaze that started Tuesday afternoon threatened several homes in the area about four miles west of Entiat.
The Chelan County sheriff's office has advised residents in Mills Canyon and Dinkleman Canyon to leave the area immediately.
Roxie Asher's husband is the Entiat Fire Chief. He and two of the couple's sons spent the day battling the fire while Asher waited anxiously in an evacuation zone issued by her husband.
"(The fire) is kind of doing its thing. It's coming down along here," Asher said.
Lee House also lives close to the flames.
"It's spooky," House said. "It guess there's a lot of words you could use for it."
Brant Stanger of the Central Washington Interagency Communication Center said Tuesday night that about 150 firefighters would be attacking the blaze overnight.
The cause is under investigation.
A shelter has been set up for evacuees at Entiat High School.
Meanwhile, a wildfire burning in Douglas County near Mansfield was 70 percent contained by Tuesday.