The pedestrians -- a 39-year-old man and a 62-year-old man -- were hit in a westbound lane of Denny Way near Fairview Avenue, according to Seattle Fire Department officials.
A witness said the men were crossing Denny in a crosswalk at about 4:30 p.m. when they were hit by a red Toyota Corolla that was attempting to turn left onto Denny from Fairview.
"Out of the corner of my eye, I see the car just ramming them. He just scooped them up," said Reynaldo Renderos, who saw the crash from his car. "They got scooped up by the car, and he must have been going 40 (miles per hour) or maybe 45."
Forrest Williams was in the same intersection when the crash happened. He said the driver was on the phone and ran a red light, slamming into pedestrians who were legally crossing the road.
"The first one rolled off and the other guy was hanging on for dear life, and he just (expletive) speeded up while the guy's hanging on and he would not slow down, like he wanted the guy to fall off so he could just keep going where he wanted to go," Williams said.
Both men were alert and conscious after the crash and both were taken to Harborview Medical Center with serious injuries, according to fire officials.
All westbound lanes of Denny were briefly closed to traffic while police investigated and the car was towed away.
It's unclear if the driver was arrested or ticketed.