The plane was delivered on Thursday and the company said the 787 will be flown to India on Friday. The plane was assembled in Everett, Wash., and then flown to South Carolina.
The company earlier this year rolled out the first 787 made in South Carolina, although that plane has not yet been delivered.
Boeing opened its $750 million assembly plant in North Charleston last year.
Air India is the fifth airline worldwide to take delivery of a 787. It has 26 more on order.