Washington State Patrol troopers say the crash happened just after 7 p.m. on State Route 104 at milepost 22.5.
A 59-year-old woman in a black Lexus was westbound on SR 104 when witnesses say she crossed the center line and slammed head-on into a red Ford Escort.
A man and woman -- both 44 years old -- inside the Escort died at the scene, as did the woman who was driving the Lexus, according to WSP Trooper Russ Winger. There were no survivors.
"It's a pretty good impact up there," Winger said. "It's pretty much head-on. There's some rotation on vehicles indicating they had pretty solid impact. It's pretty grisly"
All three victims were from the north end, and Winger said the woman in the Lexus had just dropped off her grandchild prior to the crash.
The crash happened west of Kingston near Balmoral Place NE, and that stretch of the highway was closed for several hours while troopers investigated the crash.