The 37-year-old man died Thursday afternoon at Harborview Medical Center. His name was not immediately released.
The second victim, a 25-year-old man, was located by officers at Rainier Avenue South and South Fountanelle Street with gunshot wounds to the stomach and leg. He also was taken to Harborview and is expected to survive his injuries.
Police say one man was able to flag down an officer about 11:30 p.m. Wednesday. The other was found at a nearby intersection.
Both suffered multiple gunshot wounds.
Officers located multiple shell casings on the sidewalk in the 4800 block of South Austin. Homicide detectives responded to the scene and launched an investigation.
No suspects are in custody.