Crews responded to the blaze, at the intersection of 230th Avenue and Patterson Road, at about 1:30 a.m. Sunday after receiving 911 calls from nearby residents.
Residents of neighboring homes, who were first at the scene, realized someone was trapped inside the burning structure and several of them attempted to rescue the occupant through a window, but those attempts were not successful. One rescuer sustained minor injuries and was taken to the hospital.
When firefighters arrived on scene, the mobile home was engulfed by flames. A second alarm was quickly sent out for additional support, since the area has no fire hydrants.
The fire was extinguished within 30 minutes, but crews remained at the scene for several hours to douse hot spots and conduct an investigation.
The cause of the fire was not immediately known.
No information was released about the victim of the fire, pending notification of next-of-kin.
It was the second two-alarm fire in the Orting Valley in the past three days. A previous blaze on Friday evening destroyed a barn and a small house on Orville Road. No one was hurt in that fire.