Officers and medics responded to the scene, the 300 block of 2nd Avenue Extension South, at about 11:40 a.m. after receiving a report of a victim stabbed near the Union Gospel Mission Men's Shelter.
Arriving at the scene, they found an approximately 40-year-old man with a stab wound to the abdomen. He was taken to Harborview Medical Center, where he is listed in stable condition.
A suspect was arrested at the scene.
It was not immediately known what led to the stabbing.