Officers responded to a report of multiple shots fired in the 7500 block of 15th Avenue NE just before 7:30 p.m. When they arrived, they found a man in his 40s with multiple gunshot wounds.
Medics took the man to Harborview Medical Center with life threatening injuries, according to police.
The shooter or shooters left the scene before police arrived and it's unclear what led up to the shooting.
Homicide/Assault and Gang Unit detectives are investigating.