Officers and medics responded to the scene, at 1st Avenue South and South Jackson Street, at about 1:30 a.m. Saturday after receiving a report of a fight and a man down.
When police arrived, they found the victim on the ground, unconscious and bleeding from the head. Seattle Fire Department medics stabilized the victim and rushed him to Harborview Medical Center.
A preliminary investigation found that the victim had walked from a bar with his wife and a friend to the intersection of 1st and Jackson, where two unknown suspects were arguing with one another.
Officers were told the victim said something to the men, who then turned on him. According to witnesses, the suspects punched the victim in the head multiple times, knocking him to the ground. The two suspects then proceeded to kick him in the head while he was on the ground.
The two suspects then fled the scene in a black four-door sedan. Officers searched the area but did not find them.
Anyone with information on this assault is asked to contact Seattle police.